PETCM

Key Product Details

Product Description

PETCM is a caspase-3 activator. Acts via inhibition of the oncoprotein ProT, therefore stimulates apoptosome formation and subsequent caspase-3 activation in a cytochrome c-dependent manner.

Product Specifications for PETCM

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for PETCM

The following data is based on the product molecular weight 240.52.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	8.32 mL	41.58 mL	83.15 mL
2.5 mM	1.66 mL	8.32 mL	16.63 mL
5 mM	0.83 mL	4.16 mL	8.32 mL
25 mM	0.17 mL	0.83 mL	1.66 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Nguyen and Wells Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proc.Natl.Acad.Sci.U.S.A. 2003 PMID: 12808146
• Jiang Distinctive roles of PHAP proteins and prothymosin-α in a death regulatory pathway. Science 2003 PMID: 12522243

Product Documents for PETCM