PF 750

Key Product Details

Product Description

PF 750 is an irreversible fatty acid amide hydrolase (FAAH) inhibitor (IC₅₀ = 16.2 nM) that displays no activity at a range of other serine hydrolases. Selectively inhibits FAAH within the central nervous system. Orally active.

Product Specifications for PF 750

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for PF 750

The following data is based on the product molecular weight 345.44.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.89 mL	14.47 mL	28.95 mL
5 mM	0.58 mL	2.89 mL	5.79 mL
10 mM	0.29 mL	1.45 mL	2.89 mL
50 mM	0.06 mL	0.29 mL	0.58 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Mileni Structure-guided inhibitor design for human FAAH by interspecies active site conversion. Proc.Natl.Acad.Sci.USA
• Ahn Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry 2007 PMID: 17949010

Product Documents for PF 750