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PF 750

Catalog #: 3307 Datasheet / COA / SDS

Discontinued Product

3307 has been discontinued.
View all Fatty Acid Amide Hydrolase (FAAH) Inhibitors products.
PF 750 | CAS No. 959151-50-9 | Fatty Acid Amide Hydrolase (FAAH) Inhibitors
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Description: Selective FAAH inhibitor

Chemical Name: N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide

Purity: ≥98%

Product Details
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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

PF 750 is an irreversible fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 16.2 nM) that displays no activity at a range of other serine hydrolases. Selectively inhibits FAAH within the central nervous system. Orally active.

Technical Data

M.Wt:
345.44
Formula:
C22H23N3O
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at RT
CAS No:
959151-50-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity.
    Ahn et al.
    Biochemistry, 2007;46:13019
  2. Structure-guided inhibitor design for human FAAH by interspecies active site conversion.
    Mileni et al.
    Proc.Natl.Acad.Sci.USA, 2008;105:12820

Product Datasheets

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