PHM 27 (human)

Tocris Bioscience | Catalog # 2080

Potent calcitonin agonist; endogenous analog of human VIP
Tocris Bioscience
Discontinued Product
2080 has been discontinued. View all Calcitonin and Related Receptor Agonists products.

Key Product Details

Description

Potent calcitonin agonist; endogenous analog of human VIP

Alternative Names

Peptide histidine methionine 27 (human),Human PHI 27
View all Calcitonin and Related Receptor Agonists »

Product Description

PHM 27 (human) is an endogenous peptide product of human prepro-VIP and analog of porcine PHI-27; potent agonist for the human calcitonin receptor (EC50 = 11 nM). Transgenic mice expressing the human VIP/PHM 27 gene in pancreatic β-islets display enhanced glucose-induced insulin secretion.

Product Specifications for PHM 27 (human)

Molecular Weight

2985.44

Formula

C135H214N34O40S

Storage

Desiccate at -20°C

CAS Number

87403-73-4

PubChem ID

16133840

InChI Key

YLBIOQUUAYXLJJ-WZUUGAJWSA-N

SMILES

[H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in 5% acetonitrile / water

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Background References

References are publications that support the biological activity of the product.

Product Documents for PHM 27 (human)

Certificate of Analysis

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Product Specific Notices for PHM 27 (human)

For research use only

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