(+)-Fluprostenol

Tocris Bioscience | Catalog # 4542

High affinity FP prostaglandin receptor agonist
Tocris Bioscience
Discontinued Product
4542 has been discontinued. View all Prostanoid Receptor Agonists products.

Key Product Details

Description

High affinity FP prostaglandin receptor agonist

Alternative Names

Travoprost acid
View all Prostanoid Receptor Agonists »

Product Description

(+)-Fluprostenol is a prostaglandin F2α (FP) receptor agonist (Ki = 49.9 nM; EC50 = 2.4 nM). Stimulates intracellular calcium mobilization in cloned human ocular FP receptors, rat A7r5 cells and mouse 3T3 cells (EC50 values are 17.5, 19.1 and 37.3 nM respectively). Analog of prostaglandin F2α. Isopropyl ester travaprost (Cat. No. 4218) also available.

Product Specifications for (+)-Fluprostenol

Molecular Weight

458.47

Formula

C23H29F3O6

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid

CAS Number

54276-17-4

PubChem ID

5311100

InChI Key

WWSWYXNVCBLWNZ-QIZQQNKQSA-N

SMILES

O[C@@H]1C[C@H](O)[C@H](C/C=C\CCCC(O)=O)[C@H]1/C=C/[C@@H](O)COC2=CC=CC(C(F)(F)F)=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 10mg/ml)

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Product Documents for (+)-Fluprostenol

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (+)-Fluprostenol

For research use only

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