Recombinant Human PMVK/phosphomevalonate kinase His Protein

Name: Recombinant Human PMVK/phosphomevalonate kinase His Protein
Brand: Novus Biologicals
SKU: NBP1-49168
Price: 329 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-49168

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all PMVK/phosphomevalonate kinase Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-192 of Human PMVK/phosphomevalonate kinase

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAPLGGAPRL VLLFSGKRKS GKDFVTEALQ SRLGADVCAV LRLSGPLKEQ YAQEHGLNFQ RLLDTSTYKE AFRKDMIRWG EEKRQADPGF FCRKIVEGIS QPIWLVSDTR RVSDIQWFRE AYGAVTQTVR VVALEQSRQQ RGWVFTPGVD DAESECGLDN FGDFDWVIEN HGVEQRLEEQ LENLIEFIRS RL

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

24.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human PMVK/phosphomevalonate kinase His Protein

SDS-PAGE: Recombinant Human PMVK/phosphomevalonate kinase His Protein [NBP1-49168]

SDS-Page: Recombinant Human PMVK/phosphomevalonate kinase Protein [NBP1-49168] - 15 % SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP1-49168

Formulation	20 mM Tris-HCl buffer (pH 7.5), 1 mM DTT, 10% glycerol, 0.1 M NaCl
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PMVK/phosphomevalonate kinase

Phosphomevalonate kinase, also known as PMVK, is a cytosolic enzyme. It was expressed highly in heart, liver, skeletal muscle, kidney and pancreas and slightly lower in brain, placenta, and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway. Recombinant human PMVK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

hPMK, HUMPMKI, phosphomevalonate kinase, PMKA, PMKase, PMKEC 2.7.4.2, PMKI

Gene Symbol

PMVK

Additional PMVK/phosphomevalonate kinase Products

Product Documents for Recombinant Human PMVK/phosphomevalonate kinase His Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human PMVK/phosphomevalonate kinase His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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