PNU 177864 hydrochloride
Discontinued Product
Chemical Name: N-[4-[2-(Propylamino)ethyl)phenyl]-4-(trifluoromethoxy)-benzenesulfonamide hydrochloride
Purity: ≥99%
Biological Activity
PNU 177864 hydrochloride is a highly selective dopamine D3 receptor antagonist. Induces phospholipidosis and exhibits antischizophrenic activity in vivo.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Myopathy related to administration of a cationic amphiphilic drug and the use of multidose drug distribution analysis to predict its occurrence.
Vonderfecht et al.
Toxicol.Pathol., 2004;32:318 -
Epididymal and systemic phospholipidosis in rats and dogs treated with DA D3 selective antagonist PNU-177864.
Rudmann et al.
Toxicol.Pathol., 2004;32:326
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