Pomalidomide 4'-PEG2-amine

Tocris Bioscience | Catalog # 6637

Cereblon ligand with PEG linker and terminal amine for onward chemistry
Tocris Bioscience

Key Product Details

Description

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Alternative Names

Pomalidomide - linker 1
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Product Description

Pomalidomide 4'-PEG2-amine is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG2 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was Pomalidomide - linker 1

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications for Pomalidomide 4'-PEG2-amine

Molecular Weight

440.88

Formula

C19H24N4O6.HCl

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

4-[[2-[2-(2-Aminoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride

CAS Number

2245697-87-2

PubChem ID

134812848

InChI Key

BIBZEYIXXZHGNZ-UHFFFAOYSA-N

SMILES

NCCOCCOCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

Product Documents for Pomalidomide 4'-PEG2-amine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Pomalidomide 4'-PEG2-amine

For research use only

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  • Targeted protein degradation
    Name: Sandipan Roy Chowdhury
    Species: cells
    Assay Type: In Vitro
    Cell Line/Tissue: MCF7
    Verified Customer | Posted 05/20/2020
    to make protacs
    Pomalidomide 4'-PEG2-amine 6637

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