Pomalidomide 4'-PEG4-amine

Tocris Bioscience | Catalog # 6963

Cereblon ligand with PEG linker and terminal amine for onward chemistry
Tocris Bioscience

Key Product Details

Description

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Alternative Names

Pomalidomide - linker 8
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Product Description

Pomalidomide 4'-PEG4-amine is a functionalized cereblon ligand for PROTACsup>® research and development; incorporates an E3 ligase ligand plus a PEG4 linker with terminal ethylamine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

This product has been recently renamed. The previous name for this product was Pomalidomide - linker 8

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Product Specifications for Pomalidomide 4'-PEG4-amine

Molecular Weight

528.99

Formula

C23H32N4O8.HCl

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

4-[(14-Amino-3,6,9,12-tetraoxatetradec-1-yl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione hydrochloride

CAS Number

2357105-92-9

SMILES

O=C(N(C(C1=CC=C2)=O)C3CCC(NC3=O)=O)C1=C2NCCOCCOCCOCCOCCN.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product.

There are currently no references for this product.

Product Documents for Pomalidomide 4'-PEG4-amine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Pomalidomide 4'-PEG4-amine

For research use only

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  • Key input for a Protac array targeting Cereblon E3
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 06/11/2020
    6963 was purchased along with additional PEGx linker's for an array of tool compounds to validate a bioluminescence assay

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