PP 3
Tocris Bioscience | Catalog # 2794
Key Product Details
Description
Product Description
PP 3 is a negative control for the Src kinase inhibitor, PP 2. Inhibits EGFR kinase (IC50 = 2.7 μM).
Active Analog also available.
Product Specifications for PP 3
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 21.12 | 100 | |
| Ethanol | 5.28 | 25 |
Preparing Stock Solutions for PP 3
The following data is based on the product molecular weight 211.22.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.73 mL | 23.67 mL | 47.34 mL |
| 5 mM | 0.95 mL | 4.73 mL | 9.47 mL |
| 10 mM | 0.47 mL | 2.37 mL | 4.73 mL |
| 50 mM | 0.09 mL | 0.47 mL | 0.95 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 28 publications citing the usage of this product.
- Hou PP2, a potent inhibitor of Src family kinases, protects against hippocampal CA1 pyramidal cell death after transient global brain ischemia. Neurosci.Letts. 2007 PMID: 17556100
- Traxler Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines. J.Med.Chem. 1997 PMID: 9357527
Product Documents for PP 3
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for PP 3
For research use only
Related Research Areas
Citations for PP 3
Customer Reviews for PP 3
There are currently no reviews for this product. Be the first to review PP 3 and earn rewards!
Have you used PP 3?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review