ProK

Key Product Details

Product Description

ProK is a lysine-based unnatural amino acid (UAA) used for genetic code expansion. It enables bioconjugation of fluorescent probes in E. coli or multicellular organisms.

Product Specifications for ProK

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for ProK

The following data is based on the product molecular weight 264.71.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.78 mL	18.89 mL	37.78 mL
5 mM	0.76 mL	3.78 mL	7.56 mL
10 mM	0.38 mL	1.89 mL	3.78 mL
50 mM	0.08 mL	0.38 mL	0.76 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Meineke Site-specific incorporation of two ncAAs for two-color bioorthogonal labeling and crosslinking of proteins on live mammalian cells. Cell Rep. 2020 PMID: 32579937
• Greiss Expanding the genetic code of an animal. J.Am.Chem.Soc. 2011 PMID: 21819153
• Neumann Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome. Nature 2010 PMID: 20154731
• Li Palladium-triggered deprotection chemistry for protein activation in living cells. Nat. Chem. 2014 PMID: 24651204
• Nguyen Genetic encoding and labeling of aliphatic azides and alkynes in recombinant proteins via a pyrrolysyl-tRNA Synthetase/tRNA(CUA) pair and click chemistry. J.Am.Chem.Soc. 2009 PMID: 19514718

Product Documents for ProK