PSB 0474
Tocris Bioscience | Catalog # 2715
Potent and selective P2Y6 agonist
Discontinued Product
2715 has been discontinued.
An alternative/replacement product is available:
4260. View all P2Y Receptor Agonists products.
Key Product Details
Description
Potent and selective P2Y6 agonist
Alternative Names
3-Phenacyl UDP disodium salt
Product Description
PSB 0474 is a potent and selective P2Y6 receptor agonist (EC50 values are 70, > 1000 and > 10000 nM for P2Y6, P2Y2 and P2Y4 receptors respectively). Induces contractions of rat isolated intrapulmonary arteries in vitro.
Product Specifications for PSB 0474
Molecular Weight
566.26
Formula
C17H18N2Na2O13P2
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
3-(2-Oxo-2-phenylethyl)-uridine-5'-diphosphate disodium salt
PubChem ID
54591398
InChI Key
LEICCBKKYICWFH-BWBFMJMBSA-L
SMILES
[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP(O)([O-])=O)N1C=CC(=O)N(CC(=O)C2=CC=CC=C2)C1=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.
- Mitchell Identification of contractile P2Y1, P2Y6, and P2Y12 receptors in rat intrapulmonary artery using selective ligands. J.Pharmacol.Exp.Ther. 2012 PMID: 22991416
- El-Tayeb Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4 and P2Y6 receptors. J.Med.Chem. 2006 PMID: 17125260
Product Documents for PSB 0474
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for PSB 0474
For research use only
Related Research Areas
Citations for PSB 0474
Customer Reviews for PSB 0474 (1)
4 out of 5
1 Customer Rating
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Assay Type: In VitroVerified Customer | Posted 10/21/2017in vitro brain slices, 100 nM concentration
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