PSB CB5

Tocris Bioscience | Catalog # 6372

Selective GPR18 antagonist
Tocris Bioscience

Key Product Details

Description

Selective GPR18 antagonist
View all Additional Cannabinoid-related Compounds »

Product Description

PSB CB5 is a selective GPR18 antagonist (IC50 = 0.279 μM). Exhibits >36-fold selectivity versus CB1 and GPR55 and 14-fold selectivity versus CB2 receptors. Inhibits N-Arachidonylglycine (Cat. No. 1445) induced acrosomal exocytosis in human spermatozoa.

Product Specifications for PSB CB5

Molecular Weight

384.88

Formula

C20H17ClN2O2S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(2Z)-2[[3-[(4-Chlorophenyl)methoxy]phenyl]methylene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3(2H)-one

CAS Number

1627710-30-8

PubChem ID

85469571

InChI Key

XJBQRMOGMULGPP-PDGQHHTCSA-N

SMILES

O=C(N1C(SCCC1)=N/2)C2=C\C3=CC(OCC4=CC=C(Cl)C=C4)=CC=C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 7.7 20

Preparing Stock Solutions for PSB CB5

The following data is based on the product molecular weight 384.88.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 12.99 mL 64.96 mL 129.91 mL
1 mM 2.60 mL 12.99 mL 25.98 mL
2 mM 1.30 mL 6.50 mL 12.99 mL
10 mM 0.26 mL 1.30 mL 2.60 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 7 publications citing the usage of this product.

Product Documents for PSB CB5

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PSB CB5

For research use only

Customer Reviews for PSB CB5

There are currently no reviews for this product. Be the first to review PSB CB5 and earn rewards!

Have you used PSB CB5?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card