R-BC154

Tocris Bioscience | Catalog # 6048

High affinity fluorescent α4β1/α9β1 inhibitor; mobilizes HSCs
Tocris Bioscience
Discontinued Product
6048 has been discontinued. View all Integrin Receptor Inhibitors products.

Key Product Details

Description

High affinity fluorescent α4β1/α9β1 inhibitor; mobilizes HSCs
View all Integrin Receptor Inhibitors »

Product Description

R-BC154 is a high affinity fluorescent α4β1/α9β1 inhibitor (Kd values are 12.7 and 38 nM, respectively); fluorescent version of BOP (Cat.No. 6047). Rapidly and preferentially mobilizes HSCs and progenitors in vivo. Excitation maximum, 561 nm; emissiosn maximum, 585 nm.

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Product Specifications for R-BC154

Molecular Weight

1212.37

Formula

C55H61N9O13S3.CH3CO2H

Storage

Store at -20°C

Purity

≥97% (HPLC)

Chemical Name

(4R)-4-[4-[[[[4-[3,6-Bis(diethylamino)xanthylium-9-yl]-3-sulfophenyl]sulfonyl]amino]methyl]-1H-1,2,3-triazol-1-yl]-1-(phenylsulfonyl)-L-prolyl-O-(1-pyrrolidinyl)-L-tyrosine acetate

PubChem ID

131648245

InChI Key

HZQNIDGYMDDNNP-MOVBADFXSA-N

SMILES

CCN(C1=CC2=[O+]C3=C(C(C4=C(S([O-])(=O)=O)C=C(S(=O)(NCC5=CN([C@@H]6C[C@@H](C(N[C@H](C(O)=O)CC7=CC=C(C=C7)OC(N8CCCC8)=O)=O)N(S(=O)(C9=CC=CC=C9)=O)C6)N=N5)=O)C=C4)=C2C=C1)C=CC(N(CC)CC)=C3)CC.CC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 6.06 5

Preparing Stock Solutions for R-BC154

The following data is based on the product molecular weight 1212.37.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.05 mM 16.50 mL 82.48 mL 164.97 mL
0.25 mM 3.30 mL 16.50 mL 32.99 mL
0.5 mM 1.65 mL 8.25 mL 16.50 mL
2.5 mM 0.33 mL 1.65 mL 3.30 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for R-BC154

Certificate of Analysis

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Product Specific Notices for R-BC154

For research use only

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