RAB39 Recombinant Protein Antigen

Novus Biologicals | Catalog # NBP2-13193PEP

Novus Biologicals
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Key Product Details

Source

E. coli

Applications

Antibody Competition
View all RAB39 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human RAB39A.

Source: E. coli

Amino Acid Sequence: SQRQVTREEAEKLSADCGMKYIETSA

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

Purity

>80% by SDS-PAGE and Coomassie blue staining

Predicted Molecular Mass

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications

Antibody Competition (10 - 100 molar excess)

Application Notes

This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-13193.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Protein / Peptide Type

Recombinant Protein Antigen

Formulation, Preparation, and Storage

NBP2-13193PEP
Formulation PBS and 1M Urea, pH 7.4.
Preservative No Preservative
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: RAB39

Belonging to the small GTPase superfamily/ Rab family, RAB39 plays an important role in cell formation and vesicular trafficking. More specifically, RAB39 proteins are involved in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. It also plays a role in the fusion of phagosomes with lysosomes. Additionally, the main molecular functions include GTP and nucleotide binding. RAB39 interacts with ATG5, CLN3, GABARAPL1, SH3GLB2 and STK11 and diseases include ataxia telangiectasia and malaria.

Alternate Names

rab-39, RAB39, member RAS oncogene family, RAB39A, rab-related GTP-binding protein, ras-related protein Rab-39A

Gene Symbol

RAB39A

Additional RAB39 Products

Product Documents for RAB39 Recombinant Protein Antigen

Certificate of Analysis

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Product Specific Notices for RAB39 Recombinant Protein Antigen

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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