RAGE antagonist peptide

Tocris Bioscience | Catalog # 6259

RAGE antagonist
Tocris Bioscience

Key Product Details

Description

RAGE antagonist
View all NFkB/IkB Inhibitors »

Product Description

RAGE antagonist peptide is a receptor for advanced glycation end products (RAGE) antagonist. Blocks S100P, S100A4 and HMGB-1 mediated RAGE activation in vitro and in vivo. Inhibits growth and metastasis of rat glioma tumors. Reduces cell growth and RAGE-mediated NF-κB activity in human PDAC cell lines. Inhibits effects of TDI exposure in BALB/c mice.

Product Specifications for RAGE antagonist peptide

Molecular Weight

1272.56

Formula

C57H101N13O17S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

1092460-91-7

PubChem ID

127021052

InChI Key

UPCWJIBXKJZZLN-YZLORNOTNA-N

SMILES

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(C)=O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 10 publications citing the usage of this product.

Product Documents for RAGE antagonist peptide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for RAGE antagonist peptide

For research use only

Citations for RAGE antagonist peptide

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  • Good inhibitor
    Name: Stefan Uderhardt
    Species: Mouse
    Assay Type: In Vivo
    Cell Line/Tissue: phagocyte
    Verified Customer | Posted 06/06/2020
    H20 dilution 10 μM

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