Recombinant Human RAIDD/CRADD His Protein

Novus Biologicals | Catalog # NBC1-18519

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
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Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-199 of Human RAIDD/CRADD

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLMLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

24.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human RAIDD/CRADD His Protein

SDS-PAGE: Recombinant Human RAIDD/CRADD His Protein [NBC1-18519]

SDS-PAGE: Recombinant Human RAIDD/CRADD His Protein [NBC1-18519]

SDS-Page: RAIDD Protein [NBC1-18519] - CRADD, 24.9kDa (219aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Formulation, Preparation, and Storage

NBC1-18519
Formulation 20 mM Tris-HCl buffer (pH 8.0), 20% glycerol, 1 mM DTT
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CRADD

CRADD is a 22 kDa, widely-expressed cytosolic adaptor protein. CRADD is a death domain (CARD/DD) containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. Recombinant CRADD protein was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

CASP2 and RIPK1 Domain Containing Adaptor With Death Domain

Alternate Names

RAIDD

Gene Symbol

CRADD

Additional CRADD Products

Product Documents for Recombinant Human RAIDD/CRADD His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human RAIDD/CRADD His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

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Associated Pathways

Apoptosis Signaling Pathway Apoptosis Signaling Pathway Thumbnail