Rat LILRC2 Alexa Fluor® 750-conjugated Antibody

Catalog #: AF4239S Datasheet / COA / SDS

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AF4239S-100UG

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Rat LILRC2 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Rat

Specificity

Detects rat LILRC2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant rat LILRC1 is observed.

Source

Polyclonal Sheep IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant rat LILRC2
Gly24-Asn230
Accession # AAY44812

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: LILRC2

LILRC2 (leukocyte immunoglobulin-like receptor C2) is a 35 kDa member of a family of inhibitory and stimulatory receptors (LILRs) that are expressed on hematopoietic cells. Mature rat LILRC2 is a type I transmembrane (TM) protein that is 241 amino acids (aa) in length. It contains a 207 aa extracellular domain (ECD), a 19 aa TM segment, and a short cytoplasmic tail. The ECD contains two Ig-like domains while the TM segment possesses an Arg residue. This suggests that LILRC2 is an activating receptor that may interact with Fc epsilon RI gamma and/or CD3 zeta. Cells expressing LILRC2 include neutrophils, B cells, and CD4⁺ and CD8⁺ T cells. No human or mouse LILRC2 is known.

Long Name

Leukocyte Immunoglobulin-like Receptor C2

Entrez Gene IDs

690906 (Rat)

Alternate Names

LILRC2