Reserpine

Tocris Bioscience | Catalog # 2742

Inhibitor of vesicular monoamine transport
Tocris Bioscience

Key Product Details

Description

Inhibitor of vesicular monoamine transport
View all Vesicular Monoamine Transporter Inhibitors »

Product Description

Binds the vesicular monoamine transporter (VMAT2) and inhibits transport of biogenic amines into adrenal chromaffin granules and synaptic vesicles. Causes depletion of biogenic amine stores. Antihypertensive and antipsychotic.

Product Specifications for Reserpine

Molecular Weight

608.68

Formula

C33H40N2O9

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(3β,16β,17α,18β,20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester

CAS Number

50-55-5

PubChem ID

5770

InChI Key

QEVHRUUCFGRFIF-MDEJGZGSSA-N

SMILES

[H][C@@](N4CC3)(C[C@@]([C@H]([C@@](OC)=O)[C@@H](OC)[C@H](OC(C6=CC(OC)=C(OC)C(OC)=C6)=O)C5)([H])[C@@]5([H])C4)C2=C3C1=C(N2)C=C(OC)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 6.09 10

Preparing Stock Solutions for Reserpine

The following data is based on the product molecular weight 608.68.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.43 mL 82.14 mL 164.29 mL
0.5 mM 3.29 mL 16.43 mL 32.86 mL
1 mM 1.64 mL 8.21 mL 16.43 mL
5 mM 0.33 mL 1.64 mL 3.29 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 27 publications citing the usage of this product.

Product Documents for Reserpine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Reserpine

For research use only

⚠ WARNING: This product can expose you to chemicals including Reserpine, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

Customer Reviews for Reserpine (1)

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  • Reserpine as a VMAT bloker to depleted the endogenous DA in mouse striatum
    Name: Benoit Delignat-Lavaud
    Species: Mouse
    Assay Type: Ex Vivo
    Cell Line/Tissue: striatum slices
    Verified Customer | Posted 01/04/2018
    This product work super fine in electrophysiology for blocking the VMAT. We currently use it at the concentration of 5 µM in normal ACSF.

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