RGD peptide

Tocris Bioscience | Catalog # 7723

Minimal recognition sequence for integrin binding; potent integrin inhibitor
Tocris Bioscience

Key Product Details

Description

Minimal recognition sequence for integrin binding; potent integrin inhibitor
View all Integrin Receptor Inhibitors »

Product Description

RGD peptide is a potent integrin inhibitor (IC50 values are 89, 335 and 440 nM for αvβ3, α5β1 and αvβ5, respectively). RGD is the minimal recognition sequence for integrin binding found in many extracellular matrix (ECM) and serum proteins. RGD peptide is used for directing association of various cell types with diverse biomaterials.  The functionality of RGD peptide is usually maintained throughout the processing and sterilization steps required for biomaterials synthesis. RGD peptide can be incorporated into hyaluronic acid hydrogel for human mesenchymal stem cells (hMSCs) delivery. RGD peptide significantly increases hMSC spreading and protein secretion under standard or ischemic culture conditions. RGD peptide can also be incorporated into alginate bioink for 3D bioprinting of MSCs onto cartilage templates for bone organogenesis.

Product Specifications for RGD peptide

Molecular Weight

346.34

Formula

C12H22N6O6

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

99896-85-2

PubChem ID

104802

InChI Key

IYMAXBFPHPZYIK-BQBZGAKWSA-N

SMILES

O=C(NCC(N[C@@H](CC(O)=O)C(O)=O)=O)[C@H](CCCNC(N)=N)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 10mg/ml in water

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Background References

References are publications that support the biological activity of the product.

Product Documents for RGD peptide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for RGD peptide

For research use only

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