Ritanserin

Key Product Details

Product Description

Ritanserin is a potent and long-acting 5-HT₂ receptor antagonist (K_i = 0.39 nM). Anxiolytic in vivo.

Product Specifications for Ritanserin

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Ritanserin

The following data is based on the product molecular weight 477.57.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.09 mL	10.47 mL	20.94 mL
5 mM	0.42 mL	2.09 mL	4.19 mL
10 mM	0.21 mL	1.05 mL	2.09 mL
50 mM	0.04 mL	0.21 mL	0.42 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 39 publications citing the usage of this product.

• Leysen Receptor-binding properties in vitro and in vivo of ritanserin. Mol.Pharmacol. 1985 PMID: 2860558
• Watanabe Syntheses and 5-HT₂ antagonist activity of bicyclic 1,2,4-triazol-3(2H)-one and 1,3,5-triazine-2,4(3H)-dione derivatives. J.Med.Chem. 1992 PMID: 1732528
• Janssen Pharmacology of potent and selective S₂-serotonergic antagonists. J.Cardiovasc.Pharmacol. 1985 PMID: 2412048

Product Documents for Ritanserin