Ro 64-5229

Tocris Bioscience | Catalog # 2913

Selective, non-competitive mGlu2 antagonist
Tocris Bioscience

Key Product Details

Description

Selective, non-competitive mGlu2 antagonist
View all Group II mGluR Antagonists »

Product Description

Ro 64-5229 is a selective, non-competitive mGlu2 antagonist. Inhibits GTPγ35S binding to mGlu2-containing membranes (IC50 = 0.11 μM).

Product Specifications for Ro 64-5229

Molecular Weight

352.26

Formula

C17H19Cl2N3O

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(Z)-1-[2-Cycloheptyloxy-2-(2,6-dichlorophenyl)ethenyl]-1H-1,2,4-triazole

CAS Number

246852-46-0

PubChem ID

10428048

InChI Key

STCVFKBRXOEQRF-YBEGLDIGSA-N

SMILES

ClC1=CC=CC(Cl)=C1/C(OC3CCCCCC3)=C/N2N=CN=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 35.23 100
Ethanol 35.23 100

Preparing Stock Solutions for Ro 64-5229

The following data is based on the product molecular weight 352.26.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.84 mL 14.19 mL 28.39 mL
5 mM 0.57 mL 2.84 mL 5.68 mL
10 mM 0.28 mL 1.42 mL 2.84 mL
50 mM 0.06 mL 0.28 mL 0.57 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

Product Documents for Ro 64-5229

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ro 64-5229

For research use only

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