Ro 90-7501

Tocris Bioscience | Catalog # 2408

Inhibitor of Aβ42 fibril formation
Tocris Bioscience
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Key Product Details

Description

Inhibitor of Aβ42 fibril formation

Product Description

Ro 90-7501 is an inhibitor of amyloid β42 (Aβ42) fibril assembly; reduces Aβ42-induced toxicity (EC50 = 2 μM).

Product Specifications for Ro 90-7501

Molecular Weight

340.39

Formula

C20H16N6

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine

CAS Number

293762-45-5

PubChem ID

824226

InChI Key

PAGZCEHLFCJSPV-UHFFFAOYSA-N

SMILES

NC1=CC=C(C=C1)C1=NC2=CC=C(C=C2N1)C1=NC2=CC=C(N)C=C2N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 3.4 10
DMSO 34.04 100

Preparing Stock Solutions for Ro 90-7501

The following data is based on the product molecular weight 340.39.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.94 mL 14.69 mL 29.38 mL
5 mM 0.59 mL 2.94 mL 5.88 mL
10 mM 0.29 mL 1.47 mL 2.94 mL
50 mM 0.06 mL 0.29 mL 0.59 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Ro 90-7501

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ro 90-7501

For research use only

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