RS 56812 hydrochloride
Chemical Name: (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-2-(1-methyl-1H-indol-3-yl)-2-(1-methyl-1H-indol-3-yl)-2-oxoacetamide hydrochloride
Purity: ≥99%
Biological Activity
RS 56812 hydrochloride is a highly potent and selective 5-HT3 partial agonist, with a pKi at 5-HT3 receptors in rat brain of 9.6, and greater than 1000-fold selectivity over a wide range of other neurotransmitter receptors.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
-
High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
N-(Quinuclidin-3-yl)-2-(1-methyl-1H-indol-3-yl)-2-oxoacetamide: a high affinity 5-HT3 receptor partial agonist.
Clark et al.
Bioorg.Med.Chem.Lett., 1995;5:1853
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for RS 56812 hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for RS 56812 hydrochloride include:
1 Citation: Showing 1 - 1
-
Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms.
Authors: Otvos Et al.
Mol Psychiatry 2015;7:2336
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for RS 56812 hydrochloride
There are currently no reviews for this product. Be the first to review RS 56812 hydrochloride and earn rewards!
Have you used RS 56812 hydrochloride?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
