S 2101

Key Product Details

Product Description

S 2101 is a LSD1 inhibitor (IC₅₀ = 990 nM; K_i = 610 nM). Exhibits selectivity for LSD1 over MAO-B and MAO-A (K_i values are 17 and 110 μM, respectively).

Product Specifications for S 2101

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for S 2101

The following data is based on the product molecular weight 311.75.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.21 mL	16.04 mL	32.08 mL
5 mM	0.64 mL	3.21 mL	6.42 mL
10 mM	0.32 mL	1.60 mL	3.21 mL
50 mM	0.06 mL	0.32 mL	0.64 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Mimasu Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1. Biochemistry 2010 PMID: 20568732

Product Documents for S 2101