(S)-3-Carboxy-4-hydroxyphenylglycine

Biological Activity

R-enantiomer also available.

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor sub-types.
   Hayashi et al.
   J.Neurosci., 1994;14:3370
3. Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes.
   Sekiyama et al.
   Br.J.Pharmacol., 1996;117:1493
4. Recent advances in the pharmacology of excitatory amino acids.
   Watkins et al.
   Excitatory Amino Acid Transmission. Eds. Hicks, Lo, 1987;:19-26
5. Phenylglycine derivatives as antagonists of metabotropic glutamate receptors.
   Watkins and Collingridge
   TiPS, 1994;15:333

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