S3QEL 2

Key Product Details

Product Description

Suppresses superoxide production by complex III in the mitochondria without affecting normal electron flux or cellular oxidative phosphorylation (IC₅₀ = 1.7 μM). Suppresses HIF-1α accumulation and enhances survival and function of primary pancreatic islets in vitro. Cell permeable.

Product Specifications for S3QEL 2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for S3QEL 2

The following data is based on the product molecular weight 323.44.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	15.46 mL	77.29 mL	154.59 mL
1 mM	3.09 mL	15.46 mL	30.92 mL
2 mM	1.55 mL	7.73 mL	15.46 mL
10 mM	0.31 mL	1.55 mL	3.09 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Orr Suppressors of superoxide production from mitochondrial complex III. Nat.Chem.Biol. 2015 PMID: 26368590

Product Documents for S3QEL 2