SARM1 Antibody

Novus Biologicals | Catalog # NBP3-13023

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Drosophila

Predicted:

Mouse (97%), Rat (95%), Rhesus Macaque (98%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all SARM1 Primary Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human SARM1. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for SARM1 Antibody

SARM1 Antibody

Immunocytochemistry/ Immunofluorescence: SARM1 Antibody [NBP3-13023] -

Immunocytochemistry/ Immunofluorescence: SARM1 Antibody [NBP3-13023] - SARM1 antibody detects SARM1 protein at cytoplasm and nucleus by immunofluorescent analysis.
Sample: 293T cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: SARM1 stained by SARM1 antibody (NBP3-13023) diluted at 1:500.
Blue: Fluoroshield with DAPI.
SARM1 Antibody - BSA Free

Western Blot: SARM1 Antibody [NBP3-13023] -

Whole cell extract (30 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with SARM1 antibody (NBP3-13023) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
SARM1 Antibody - BSA Free

Western Blot: SARM1 Antibody [NBP3-13023] -

Mouse tissue extract (50 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with SARM1 antibody (NBP3-13023) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for SARM1 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1% BSA, 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SARM1

Toll-like receptors (TLRs) play an essential role in the detection and elimination of invading microbes. They are type-1 transmembrane receptors, containing extracellular leucine rich repeats and an intracellular Toll/interleukin-1 receptor (TIR) domain. Upon stimulation, these receptors interact with specific TIR domain-containing adaptor proteins. Five such adaptors have been discovered to date, MyD88, Mal (MyD88 adaptor-like)/TIRAP (TIR domain-containing adaptor protein), Trif (TIR-domain-containing adaptor inducing interferon-beta), TRAM (Trif-related adaptor molecule) and SARM (SAM and ARM-containing protein). Different TLRs use different combinations of these adaptors, leading to the activation of common and unique pathways involved in the elimination of the invading microbe.

Long Name

Sterile alpha and TIR Motif Containing 1

Alternate Names

SAMD2

Gene Symbol

SARM1

Additional SARM1 Products

Product Documents for SARM1 Antibody

Certificate of Analysis

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Product Specific Notices for SARM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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