SBP1

Tocris Bioscience | Catalog # 7233

ACE2 derived peptide; binds SARS-CoV-2 spike protein receptor binding domain
Tocris Bioscience
Discontinued Product
7233 has been discontinued. View all Other ACE2 Compounds products.

Key Product Details

Description

ACE2 derived peptide; binds SARS-CoV-2 spike protein receptor binding domain
View all Other ACE2 Compounds »

Product Description

SBP1 is a human ACE2 receptor-derived 23-amino acid peptide. Binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et al preprint publication).

Please note - unpublished, in-house data suggests approximately 75-fold lower affinity for insect-derived SARS-CoV-2 RBD than reported by Zhang et al.

Product Specifications for SBP1

Molecular Weight

2802.05

Formula

C127H185N31O41

Storage

Store at -20°C

Purity

≥95% (HPLC)

InChI Key

VTVUOJBJFPPIBF-SDBILGLNSA-N

SMILES

O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(N)=O)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@@H](C)CC)N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in PBS

Calculators

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Background References

References are publications that support the biological activity of the product.

  • Zhang Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD. BioRxiv - Paper not yet peer reviewed

Product Documents for SBP1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SBP1

For research use only

Related Research Areas

Infectious Diseases

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