SenTraGor™

Tocris Bioscience | Catalog # 7555

Reagent for staining and detection of lipofuscin in senescent cells
Tocris Bioscience
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Key Product Details

Description

Reagent for staining and detection of lipofuscin in senescent cells

Product Description

SenTraGor is a reagent for detecting lipofuscin in senescent cells. A highly lipophilic and biotinylated analog of Sudan Black B; can be detected using an anti-biotin antibody. Can be used in vivo and in vitro in any biological material including cell cultures, fresh and frozen tissues, and fixed embedded samples. Compatible with immunohistochemistry, flow cytometry and immunofluorescence analysis.

SenTraGor™ is a trademark of University of Manchester.

Licensing Information

Sold under license from University of Manchester Innovation Factory

Product Specifications for SenTraGor™

Molecular Weight

698.85

Formula

C39H38N8O3S

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(2-Methyl-6-((E)-(4-((E)-phenyldiazenyl)naphthalen-1-yl)diazenyl)-2,3-dihydro-1H-perimidin-2-yl)methyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate

CAS Number

2171036-89-6

PubChem ID

166603878

InChI Key

NCGWNTJOKSLKQK-SPNFGPMXSA-N

SMILES

[H][C@]12CS[C@H]([C@]1(NC(N2)=O)[H])CCCCC(OCC3(C)NC4=CC=CC5=C4C(N3)=CC=C5/N=N/C6=CC=C(C7=C6C=CC=C7)/N=N/C8=CC=CC=C8)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 13.98 20
Ethanol 6.99 10 with gentle warming

Preparing Stock Solutions for SenTraGor™

The following data is based on the product molecular weight 698.85.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 7.15 mL 35.77 mL 71.55 mL
1 mM 1.43 mL 7.15 mL 14.31 mL
2 mM 0.72 mL 3.58 mL 7.15 mL
10 mM 0.14 mL 0.72 mL 1.43 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for SenTraGor™

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SenTraGor™

For research use only

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