Shz 1

Tocris Bioscience | Catalog # 4923

Activator of early cardiac genes in pluripotent stem cells; induces differentiation in M-PBMCs
Tocris Bioscience
Discontinued Product
4923 has been discontinued. View all Compounds for Stem Cell Differentiation products.

Key Product Details

Description

Activator of early cardiac genes in pluripotent stem cells; induces differentiation in M-PBMCs

Product Description

Shz 1 is an activator of early cardiac genes (including Nkx2.5) in pluripotent stem cells. Induces phenotypic differentiation in human mobilized peripheral blood mononuclear cells. Enhances myocardial regenerative repair by stem cells in a rat myocardial cryoinjury model.

Product Specifications for Shz 1

Molecular Weight

355.21

Formula

C13H11BrN2O3S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide benzenesulfonic acid

CAS Number

326886-05-9

PubChem ID

5334954

InChI Key

YFHOVIHRHCFCIR-MDZDMXLPSA-N

SMILES

OC1=C(/C=N/NS(C2=CC=CC=C2)(=O)=O)C=C(Br)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 35.52 100
Ethanol 17.76 50

Preparing Stock Solutions for Shz 1

The following data is based on the product molecular weight 355.21.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.82 mL 14.08 mL 28.15 mL
5 mM 0.56 mL 2.82 mL 5.63 mL
10 mM 0.28 mL 1.41 mL 2.82 mL
50 mM 0.06 mL 0.28 mL 0.56 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for Shz 1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Shz 1

For research use only

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