SID 26681509

Tocris Bioscience | Catalog # 3625

Cathepsin L inhibitor
Tocris Bioscience

Key Product Details

Description

Cathepsin L inhibitor
View all Synthetic Cathepsin Inhibitors »

Product Description

SID 26681509 is a potent and reversible human cathepsin L inhibitor (IC50 = 56 nM). Displays no inhibitory activity at cathepsin G. Antimalarial; inhibits leishmaniasis.

Product Specifications for SID 26681509

Molecular Weight

539.65

Formula

C27H33N5O5S

Storage

Store at -20°C

Purity

≥97% (HPLC)

Chemical Name

N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophan-2-[[[2-[(2-ethylphenyl)amino]-2-oxoethyl]thio]carbonyl]hydrazide

CAS Number

958772-66-2

PubChem ID

16725315

InChI Key

OTIWAYTTYNFEKL-QFIPXVFZSA-N

SMILES

O=C(NNC(SCC(NC1=C(CC)C=CC=C1)=O)=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(OC(C)(C)C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 26.98 50
Ethanol 5.4 10

Preparing Stock Solutions for SID 26681509

The following data is based on the product molecular weight 539.65.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.71 mL 18.53 mL 37.06 mL
2.5 mM 0.74 mL 3.71 mL 7.41 mL
5 mM 0.37 mL 1.85 mL 3.71 mL
25 mM 0.07 mL 0.37 mL 0.74 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

Product Documents for SID 26681509

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SID 26681509

For research use only

Customer Reviews for SID 26681509 (1)

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  • test
    Name: Dongzheng Gai
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Primary macrophage
    Verified Customer | Posted 10/04/2021
    The cathepsin L inhibitor SID 26681509 works excellent in suppressing the cell lysate cathepsin L activity.
    SID 26681509 3625

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