The CA125 antigen, also known as MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. Expression of isoforms, proteolytic cleavage, and heavy N- and O- linked glycosylation produce forms of human CA125 that can vary from 200-5000 kDa in size. It inhibits NK cell activity, which is thought to contribute to immune evasion in peritoneal cancer and pregnancy.
Simple Plex Control for Human CA125/MUC16
R&D Systems | Catalog # 898073
Control for use with Human CA125/MUC16 Simple Plex Cartridge Kit
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Key Product Details
Species
Human
Applications
Control, Simple Plex Automated Immunoassay
Product Summary for Simple Plex Control for Human CA125/MUC16
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human CA125/MUC16 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
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Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: CA125/MUC16
Long Name
Ovarian Cancer Antigen CA125
Alternate Names
MUC16
Entrez Gene IDs
94025 (Human)
Gene Symbol
MUC16
Additional CA125/MUC16 Products
Product Documents for Simple Plex Control for Human CA125/MUC16
Certificate of Analysis
To download a Certificate of Analysis, please enter your Simple Plex catalog number and lot number in the search boxes below.
Product Specific Notices for Simple Plex Control for Human CA125/MUC16
For research use only
Related Research Areas
Citations for Simple Plex Control for Human CA125/MUC16
View all citations for the Simple Plex platform on Bio-Techne.com.
Please visit our Instrument Citation Database on Bio-Techne.com to search our collection of scientific articles that feature our instruments.
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