Simple Plex Control for Human Granzyme A

R&D Systems | Catalog # 898410

Control for use with Human and Non-Human Primate Granzyme A Simple Plex Cartridge Kit
R&D Systems
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Key Product Details

Species

Human, Non-human Primate

Applications

Control, Simple Plex Automated Immunoassay

Product Summary for Simple Plex Control for Human Granzyme A

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human and NHP Granzyme A concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
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Formulation, Preparation, and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: Granzyme A

Granzyme family serine proteases are stored in the granules of cytotoxic T lymphocytes and natural killer cells. Granzymes contain one S1 protease domain and are synthesized as preproproteins. Granzymes are released toward pathogen infected or transformed target cells during cellular immune reactions. Target cell entry by granzymes is through perforin channels. Granzymes trigger apoptosis by caspase-dependent and -independent mechanisms. There are five granzymes (A, B, G, H and K) in human and many more in mouse and rat.

Alternate Names

CTL Tryptase, CTLA3, Fragmentin-1, GZMA, HF, HFSP

Entrez Gene IDs

3001 (Human); 14938 (Mouse); 266708 (Rat)

Gene Symbol

GZMA

Additional Granzyme A Products

Product Documents for Simple Plex Control for Human Granzyme A

Certificate of Analysis

To download a Certificate of Analysis, please enter your Simple Plex catalog number and lot number in the search boxes below.

Product Specific Notices for Simple Plex Control for Human Granzyme A

For research use only

Citations for Simple Plex Control for Human Granzyme A

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