Simple Plex Control for Human IL-17/IL-17A

Name: Simple Plex Control for Human IL-17/IL-17A
Brand: R&D Systems
SKU: 894959
Price: 150 USD
Availability: InStock

R&D Systems | Catalog # 894959

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Citations

Product Documents

Control for use with Human and Non-Human Primate IL-17/IL-17A Simple Plex Cartridge Kit

Product Summary
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human, Non-human Primate

Applications

Control, Simple Plex Automated Immunoassay

Product Summary for Simple Plex Control for Human IL-17/IL-17A

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human and NHP IL-17/IL-17A concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Background: IL-17/IL-17A

IL-17/IL-17A is a homodimeric cytokine that is secreted by IL-23 activated Th17 and Tc17 cells. It is upregulated during inflammation and contributes to disease severity by enhancing neutrophil infiltration and the production of pro-inflammatory chemokines. IL-17A can additionally form bioactive heterodimers with IL-17F. IL-17A and the IL-17A/F heterodimer signal through widely expressed receptor complexes containing IL-17 RA and IL-17 RC.