The synuclein family includes synuclein-alpha, -beta, and -gamma, and synoretin. These small, highly conserved proteins are localized predominantly in the brain, concentrated in presynaptic nerve terminals. Synuclein-alpha is normally a soluble protein. Abnormal synuclein-alpha forms filamentous inclusions (Lewy bodies and Lewy neurites) in several neurodegenerative diseases, including Parkinson's disease (PD), dementia with Lewy bodies, and Alzheimer's disease. Synucleins beta and gamma (synoretin) associate with synuclein-alpha and inhibit its aggregation.
Simple Plex Control for Human/Mouse/Rat beta-Synuclein
R&D Systems | Catalog # 897123
Control for use with Human/Mouse/Rat beta-Synuclein Simple Plex Assay Cartridge Kit
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Key Product Details
Species
Human, Mouse, Rat
Applications
Simple Plex Automated Immunoassay
Product Summary for Simple Plex Control for Human/Mouse/Rat beta-Synuclein
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human beta-Synuclein concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
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Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: beta-Synuclein
Alternate Names
SNCB, Synuclein-beta
Gene Symbol
SNCB
Additional beta-Synuclein Products
Product Documents for Simple Plex Control for Human/Mouse/Rat beta-Synuclein
Certificate of Analysis
To download a Certificate of Analysis, please enter your Simple Plex catalog number and lot number in the search boxes below.
Product Specific Notices for Simple Plex Control for Human/Mouse/Rat beta-Synuclein
For research use only
Citations for Simple Plex Control for Human/Mouse/Rat beta-Synuclein
View all citations for the Simple Plex platform on Bio-Techne.com.
Please visit our Instrument Citation Database on Bio-Techne.com to search our collection of scientific articles that feature our instruments.
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