Simple Plex Control for Human Procalcitonin

R&D Systems | Catalog # 898497

Control for use with Human Procalcitonin Simple Plex Cartridge Kit
R&D Systems

Key Product Details

Species

Human

Applications

Control, Simple Plex Automated Immunoassay

Product Summary for Simple Plex Control for Human Procalcitonin

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human Procalcitonin concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Formulation, Preparation, and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: Procalcitonin

Procalcitonin (PCT) is a 116 amino acid residue peptide with molecular weight of about 13 kDa. PCT itself has no known hormonal activity. PCT belongs to a group of related proteins including calcitonin gene-related peptides I and II, amylin, adrenomodulin and calcitonin (CAPA peptide family). PCT, like other peptides of CAPA family, appears from the common precursor pre-procalcitonin consisting of 141 amino acids by removal of 25 amino acids from the N-terminus. PCT undergoes successive cleavages to form three molecules: N-terminal fragment (55 a.a.), calcitonin (32 a.a.) and katacalcin (21 a.a.). Under normal metabolic conditions, PCT is only present in the C cells of the thyroid gland. In bacterial infection and sepsis, however, intact PCT is found in the blood and, more importantly, its level is related to the severity of bacterial sepsis. Today, PCT is considered to be one of the earliest and most specific markers of sepsis.

Alternate Names

CALC1, CALCA, Calcitonin 1, calcitonin gene-related peptide 1, CGRP, Katacalcin

Entrez Gene IDs

796 (Human); 12310 (Mouse); 24241 (Rat)

Gene Symbol

CALCA

Additional Procalcitonin Products

Product Documents for Simple Plex Control for Human Procalcitonin

Certificate of Analysis

To download a Certificate of Analysis, please enter your Simple Plex catalog number and lot number in the search boxes below.

Product Specific Notices for Simple Plex Control for Human Procalcitonin

For research use only

Citations for Simple Plex Control for Human Procalcitonin

View all citations for the Simple Plex platform on Bio-Techne.com.

Please visit our Instrument Citation Database on Bio-Techne.com to search our collection of scientific articles that feature our instruments.

Customer Reviews for Simple Plex Control for Human Procalcitonin

There are currently no reviews for this product. Be the first to review Simple Plex Control for Human Procalcitonin and earn rewards!

Have you used Simple Plex Control for Human Procalcitonin?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card