SLIGRL-NH2
Tocris Bioscience | Catalog # 1468
PAR2-activating peptide
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Key Product Details
Description
PAR2-activating peptide
Product Description
SLIGRL-NH2 is an agonist peptide derived from the N-terminus of protease-activated receptor-2 (PAR2). Activates PAR2 (EC50 ~ 5 μM) and facilitates gastrointestinal transit in mice in vivo.Control Peptide also available.
Product Specifications for SLIGRL-NH2
Molecular Weight
656.82
Formula
C29H56N10O7
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
171436-38-7
PubChem ID
9831050
InChI Key
SGPMJRPYYIJZPC-JYAZKYGWSA-N
SMILES
[H]N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 32 publications citing the usage of this product.
- Kawabata In vivo evidence that protease-activated receptors 1 and 2 modulate gastrointestinal transit in the mouse. Br.J.Pharmacol. 2001 PMID: 11498505
- Nystedt Molecular cloning of a potential proteinase activated receptor. Proc.Natl.Acad.Sci.U.S.A. 1994 PMID: 7937743
- Al-Ani Detection of functional receptors for the proteinase-activated-receptor-2-activating polypeptide, SLIGRL-NH2, in rat vascular and gastric smooth muscle. Can.J.Physiol.Pharmacol. 1995 PMID: 8564891
Product Documents for SLIGRL-NH2
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for SLIGRL-NH2
For research use only
Citations for SLIGRL-NH2
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Species: HumanAssay Type: In VitroCell Line/Tissue: Smooth Muscle CellsVerified Customer | Posted 11/20/2019Inv-vitro stimulation of PAR2 receptor in Smooth muscle cells
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