SR 0987

Tocris Bioscience | Catalog # 5868

T cell-specific RORγ (RORγt) agonist
Tocris Bioscience

Key Product Details

Description

T cell-specific RORγ (RORγt) agonist
View all Nuclear Receptor Agonists »

Product Description

SR 0987 is a T cell-specific RORγ (RORγt) agonist (EC50 = 800 nM in a gene reporter assay). Induces IL-17 expression and decreases PD-1 expression in T cells in vitro.

Product Specifications for SR 0987

Molecular Weight

397.70

Formula

C16H10ClF6NO2

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2-Chloro-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzamide

CAS Number

303126-97-8

PubChem ID

2323435

InChI Key

IZVBONMVWLTLNT-UHFFFAOYSA-N

SMILES

OC(C(F)(F)F)(C(F)(F)F)C1=CC=C(C=C1)NC(C2=C(C=CC=C2)Cl)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.77 100
Ethanol 39.77 100

Preparing Stock Solutions for SR 0987

The following data is based on the product molecular weight 397.70.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.51 mL 12.57 mL 25.14 mL
5 mM 0.50 mL 2.51 mL 5.03 mL
10 mM 0.25 mL 1.26 mL 2.51 mL
50 mM 0.05 mL 0.25 mL 0.50 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for SR 0987

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SR 0987

For research use only

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