ST 1936 oxalate

Key Product Details

Product Description

ST 1936 oxalate is a high affinity, selective agonist of 5-HT₆ receptors (K_i values are 13, 168, and 245 nM for human 5-HT₆, 5-HT₇ and 5-HT_2B receptors respectively). Displays moderate affinity for human α₂ adrenergic receptors (K_i = 300 nM). Shown to increase Ca²⁺ concentration and phosphorylation of Fyn kinase, and regulate the activation of ERK1/2 in cloned cells.

Product Specifications for ST 1936 oxalate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for ST 1936 oxalate

The following data is based on the product molecular weight 326.78.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.06 mL	15.30 mL	30.60 mL
5 mM	0.61 mL	3.06 mL	6.12 mL
10 mM	0.31 mL	1.53 mL	3.06 mL
50 mM	0.06 mL	0.31 mL	0.61 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Valentini A microdialysis study of ST1936, a novel 5-HT6 receptor agonist. Neuropharmacology 2011 PMID: 21185318
• Riccioni ST1936 stimulates cAMP, Ca²⁺, ERK1/2 and Fyn kinase through a full activation of cloned 5-HT₆ receptors. Eur.J.Pharmacol. 2011 PMID: 21549693

Product Documents for ST 1936 oxalate