Recombinant Human SUGT1 His Protein

Novus Biologicals | Catalog # NBP1-50979

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
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Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 115-365 of Human SUGT1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MHRVGQAGLQ LLTSSDPPAL DSQSAGITGA DANFSVWIKR CQEAQNGSES EVWTHQSKIK YDWYQTESQV VITLMIKNVQ KNDVNVEFSE KELSALVKLP SGEDYNLKLE LLHPIIPEQS TFKVLSTKIE IKLKKPEAVR WEKLEGQGDV PTPKQFVADV KNLYPSSSPY TRNWDKLVGE IKEEEKNEKL EGDAALNRLF QQIYSDGSDE VKRAMNKSFM ESGGTVLSTN WSDVGKRKVE INPPDDMEWK KY

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

30.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human SUGT1 His Protein

SDS-PAGE: Recombinant Human SUGT1 His Protein [NBP1-50979]

SDS-PAGE: Recombinant Human SUGT1 His Protein [NBP1-50979]

SDS-Page: Recombinant Human SUGT1 Protein [NBP1-50979] - 15 % SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP1-50979
Formulation 20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 1 mM DTT, 0.1 M NaCl
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SUGT1

SUGT1, also known as suppressor of G2 allele of SKP1, is a homolog of the yeast protein SGT1, a regulator of the cell cycle that is essential for G1/S and G2/M transitions. It contains a CS domain, a SGS domain, a p23 domain and three tetratricopeptide repeats (TPR). This protein associates with Skp1 p19 and CUL-1, subunits of the SCF ubiquitin ligase complex, and is thought to play a role in protein degradation. In addition, it is required for the kinetochores assembly, and has function as a co-chaperone for HSP90. Recombinant human SUGT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

Protein 40-6-3, putative 40-6-3 protein, SGT1, SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae), SGT1B protein, suppressor of G2 allele of SKP1 homolog, suppressor of G2 allele of SKP1, S. cerevisiae, homolog of

Gene Symbol

SUGT1

Additional SUGT1 Products

Product Documents for Recombinant Human SUGT1 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human SUGT1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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