T3

Tocris Bioscience | Catalog # 6666

Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells
Tocris Bioscience

Key Product Details

Description

Thyroid hormone; also promotes differentiation of oligodendroglial precursor cells
View all Compounds for Stem Cell Differentiation »

Product Description

T3 is a thyroid hormone. Promotes differentiation of oligodendroglial precursor cells in neonatal rats and promotes maturation of hiPSC-derived cardiomyocytes. Also specifies cone cell subtype in retinal cell differentiation protocols. T3 is used to generate cortical spheroids and β cells (see protocol below) from hPSCs.

T3 synthesized to Ancillary Material Grade also available.

For more information about how T3 may be used, see our protocol: Generation of β cells from hPSCs

Product Specifications for T3

Molecular Weight

650.97

Formula

C15H12I3NO4

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

O-(4-Hydroxy-3-iodophenyl-3,5-diiodo-L-tyrosine

CAS Number

6893-02-3

PubChem ID

5920

InChI Key

AUYYCJSJGJYCDS-LBPRGKRZSA-N

SMILES

N[C@H](C(O)=O)CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(C=C2)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.55 50

Preparing Stock Solutions for T3

The following data is based on the product molecular weight 650.97.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.07 mL 15.36 mL 30.72 mL
2.5 mM 0.61 mL 3.07 mL 6.14 mL
5 mM 0.31 mL 1.54 mL 3.07 mL
25 mM 0.06 mL 0.31 mL 0.61 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

Product Documents for T3

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for T3

For research use only

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