Tafluprost
Tocris Bioscience | Catalog # 6427
Very high affinity FP receptor agonist
Discontinued Product
6427 has been discontinued.
View all Prostanoid Receptor Agonists products.
Key Product Details
Description
Very high affinity FP receptor agonist
Product Description
Tafluprost is a very high affinity FP receptor agonist (Ki = 0.4 nM). Reduces intraocular pressure (IOP) in animal models of ocular hypertension and normal animals.
Product Specifications for Tafluprost
Molecular Weight
452.53
Formula
C25H34F2O5
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
1-Methylethyl (5-Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoate
CAS Number
209860-87-7
PubChem ID
9868491
InChI Key
WSNODXPBBALQOF-VEJSHDCNSA-N
SMILES
O[C@@H]1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](/C=C/C(F)(F)COC2=CC=CC=C2)[C@H](O)C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble in methyl acetate (supplied pre-dissolved -10mg/ml) |
Calculators
Background References
References are publications that support the biological activity of the product.
- Takagi Pharmacological characteristics of AFP-168 (tafluprost), a new prostanoid FP receptor agonist, as an ocular hypotensive drug. Exp.Eye Res. 2004 PMID: 15037111
Product Documents for Tafluprost
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Tafluprost
For research use only
Related Research Areas
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