TAK 21d

Key Product Details

Product Description

TAK 21d is a potent FAAH inhibitor; (IC₅₀ values are 0.28 and 0.72 nM, at rat and human FAAH respectively). Displays analgesic effects in vivo models of neuropathic and inflammatory pain. Brain penetrant.

Product Specifications for TAK 21d

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for TAK 21d

The following data is based on the product molecular weight 397.38.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	12.58 mL	62.91 mL	125.82 mL
1 mM	2.52 mL	12.58 mL	25.16 mL
2 mM	1.26 mL	6.29 mL	12.58 mL
10 mM	0.25 mL	1.26 mL	2.52 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Kono Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors. Bioorg.Med.Chem. 2014 PMID: 24440478

Product Documents for TAK 21d