Tamoxifen

Tocris Bioscience | Catalog # 6342

Estrogen receptor partial agonist/antagonist
Tocris Bioscience

Key Product Details

Description

Estrogen receptor partial agonist/antagonist
View all Estrogen and Related Receptor Modulators »

Product Description

Tamoxifen is a selective estrogen receptor modulator (SERM). Exhibits antiestrogenic effects in mammary tissue and estrogen-like effects in bone. Anticancer. Tamoxifen citrate (Cat.No. 0999) is also available.

Product Specifications for Tamoxifen

Molecular Weight

371.51

Formula

C26H29NO

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethylethanamine

CAS Number

10540-29-1

PubChem ID

2733526

InChI Key

NKANXQFJJICGDU-QPLCGJKRSA-N

SMILES

CN(C)CCOC1=CC=C(C=C1)/C(C2=CC=CC=C2)=C(CC)\C3=CC=CC=C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 7.43 20
Ethanol 37.15 100

Preparing Stock Solutions for Tamoxifen

The following data is based on the product molecular weight 371.51.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.69 mL 13.46 mL 26.92 mL
5 mM 0.54 mL 2.69 mL 5.38 mL
10 mM 0.27 mL 1.35 mL 2.69 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 118 publications citing the usage of this product.

Product Documents for Tamoxifen

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Tamoxifen

For research use only

⚠ WARNING: This product can expose you to chemicals including Tamoxifen and its salts, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov

Customer Reviews for Tamoxifen (2)

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  • Tamoxifen
    Name: Anonymous
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Breast cancer cell MCF-7
    Verified Customer | Posted 09/30/2025
    Tamoxifen (1 uM) was used to maintain tamoxifen resistant breast cancer cell line, MCF7 TAMR-1. The line exhibited higher levels of antioxidant enzyme HO-1 compared to parental line.
    Tamoxifen 6342
  • Tamoxifen for ERT-cre mice
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Verified Customer | Posted 05/23/2019
    given 180mg/kg/day i.p., injections 24 hours apart. dissolved 30mg/ml in 1:9 etoh and sunflower seed oil
    given for tamoxifen-inducible cre mice. saw excellent GFP expression with 2 doses.
    Tamoxifen 6342

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