TAT 14

Tocris Bioscience | Catalog # 4811

Nrf2 pathway activator; blocks Nrf2/Keap1 interaction
Tocris Bioscience
Discontinued Product
4811 has been discontinued. View all Nrf2 Activators products.

Key Product Details

Description

Nrf2 pathway activator; blocks Nrf2/Keap1 interaction

Product Description

TAT 14 is a Nrf2 activator; inhibits Nrf2/Keap1 interaction. Induces upregulation of Nrf2 pathway downstream gene expression including heme-oxygenase 1. Suppresses LPS-induced TNF-α expression in THP-1 cells.

Product Specifications for TAT 14

Molecular Weight

3173.60

Formula

C137H230N48O39

Storage

Store at -20°C

CAS Number

1362661-34-4

PubChem ID

60150581

InChI Key

NBFQPSCRGQGZEP-YBKRDZSWSA-N

SMILES

[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product.

Product Documents for TAT 14

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TAT 14

For research use only

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