TCS 183

Tocris Bioscience | Catalog # 2236

Fragment 1-13 of GSK-3β sequence
Tocris Bioscience
Discontinued Product
2236 has been discontinued. View all Additional GSK-3 Peptides products.

Key Product Details

Description

Fragment 1-13 of GSK-3β sequence
View all Additional GSK-3 Peptides »

Product Description

TCS 183 is a fragment 1-13 of human and mouse GSK-3β sequence. Potentially useful as a competitive inhibitor of GSK-3β (Ser9) phosphorylation.

Control Peptide also available.

Product Specifications for TCS 183

Molecular Weight

1425.58

Formula

C58H96N20O20S

Storage

Desiccate at -20°C

PubChem ID

90488752

InChI Key

CPHAYBWPVDHKAJ-BOGMMOMNSA-N

SMILES

[H]N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 16 publications citing the usage of this product.

Product Documents for TCS 183

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TCS 183

For research use only

Customer Reviews for TCS 183 (1)

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  • TCS-183 efficiently blocks Wnt/ beta-catenin pathway in vivo
    Name: Jessica Vargas
    Species: Mouse
    Assay Type: In Vivo
    Cell Line/Tissue: Brain
    Verified Customer | Posted 01/06/2018
    TCS-183, a competitive inhibitor of the inactivating GSK-3 beta phosphorylation, was used to block the activation of Wnt/ beta-catenin pathway in vivo. 300 micro-Molar of TCS-183 was diluted in sterile artificial cerebrospinal fluid and 0.01% DMSO. Chronic intracerebral delivery of the product was achieved via an osmotic mini-pump implanted on C57BL/6 mice.
    TCS 183 2236

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