Tetrindole mesylate
Discontinued Product
Chemical Name: 2,3,3a,4,5,6-Hexahydro-8-cyclohexyl-1H-pyrazino[3,2,1-j,k]carbazole mesylate
Purity: ≥99%
Biological Activity
Tetrindole mesylate is a novel antidepressant, a selective inhibitor of MAO-A.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Resolution, EPC-syntheses, absolute stereochemistry, and pharmacology of the (S)-(+)- and (R)-(-)-isomers of the MAO-A inhibitor tetrindole hydrochloride.
Bos et al.
Arch.Pharm. (Wenheim), 1995;328:619 -
Hemodynamic effects of tetrindol in alert normotensive mice and rats after blockade of nitric oxide synthesis.
Korshunov et al.
Bull.Exp.Biol.Med., 2000;130:777 -
Monoamine oxidase inhibition by novel antidepressant tetrindole.
Medvedev et al.
Biochem.Pharmacol., 1994;47:303
Product Datasheets
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Citation for Tetrindole mesylate
The citations listed below are publications that use Tocris products. Selected citations for Tetrindole mesylate include:
1 Citation: Showing 1 - 1
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Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C.
Authors: Ulferts Et al.
Antimicrob Agents Chemother 2016;60:2627
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