TG 4-155

Tocris Bioscience | Catalog # 5052

High affinity and selective EP2 receptor antagonist
Tocris Bioscience
Discontinued Product
5052 has been discontinued. View all Prostanoid Receptor Antagonists products.

Key Product Details

Description

High affinity and selective EP2 receptor antagonist
View all Prostanoid Receptor Antagonists »

Product Description

TG 4-155 is a high affinity and selective EP2 receptor antagonist (KB values are 2.4 and 34.5 nM for EP2 and DP1 receptors respectively). Exhibits >500-fold selectivity for EP2 over other prostanoid receptors. Inhibits butaprost-induced proinflammatory cytokine production, cell proliferation and invasion of PC-3 cells in vitro.

Product Specifications for TG 4-155

Molecular Weight

394.46

Formula

C23H26N2O4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(2E)-N-[2-(2-Methyl-1H-indol-1-yl)ethyl]-3-(3,4,5-trimethoxyphenyl)-2-propenamide

CAS Number

1164462-05-8

PubChem ID

5886965

InChI Key

YBHUXHFZLMFETJ-MDZDMXLPSA-N

SMILES

CC2=CC1=CC=CC=C1N2CCNC(/C=C/C3=CC(OC)=C(OC)C(OC)=C3)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.45 100
Ethanol 7.89 20

Preparing Stock Solutions for TG 4-155

The following data is based on the product molecular weight 394.46.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.54 mL 12.68 mL 25.35 mL
5 mM 0.51 mL 2.54 mL 5.07 mL
10 mM 0.25 mL 1.27 mL 2.54 mL
50 mM 0.05 mL 0.25 mL 0.51 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Product Documents for TG 4-155

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TG 4-155

For research use only

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