TH 10785

Key Product Details

Product Description

TH 10785 is an 8-oxo guanine DNA glycosylase 1 (OGG1) activator. It binds in the active site of OGG1 and increases its recruitment to oxidative DNA damage and its repair.

Product Specifications for TH 10785

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for TH 10785

The following data is based on the product molecular weight 267.38.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.74 mL	18.70 mL	37.40 mL
5 mM	0.75 mL	3.74 mL	7.48 mL
10 mM	0.37 mL	1.87 mL	3.74 mL
50 mM	0.07 mL	0.37 mL	0.75 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Michel Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science 2022 PMID: 35737787

Product Documents for TH 10785