Tiotidine

Key Product Details

Product Description

Tiotidine is a potent histamine H₂-receptor antagonist with negligible activity against H₁- and H₃- receptors.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Product Specifications for Tiotidine

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Tiotidine

The following data is based on the product molecular weight 312.41.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.20 mL	16.00 mL	32.01 mL
5 mM	0.64 mL	3.20 mL	6.40 mL
10 mM	0.32 mL	1.60 mL	3.20 mL
50 mM	0.06 mL	0.32 mL	0.64 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 43 publications citing the usage of this product.

• Trzeciakowski and Levi The cardiac pharmacology of tiotidine (ICI 125,211): A new histamine H₂- receptor antagonist. J.Pharmacol.Exp.Ther. 1980 PMID: 6105207
• Yellin ICI 125,211: A new gastric antisecretory agent acting on histamine H₂- receptors. Life Sci. 1979 PMID: 43449
• Hill Distribution, properties, and functional characteristics of three classes of histamine receptor. Pharmacol.Rev. 1990 PMID: 2164693

Product Documents for Tiotidine